The invitroTKdata
R package contains a collection of
datasets containing a variety of in vitro toxicokinetic
measurements including – but not limited to – chemical fraction unbound
in the presence of plasma (\(f_{up}\)),
intrinsic hepatic clearance (\(Cl_{int}\)), and membrane permeability for
oral absorption (Caco2). The datasets provided by the package were
processed and analyzed with the companion invitroTKstats
package
Notification: Datasets within this package have
all been processed with various prototype versions of the
invitroTKstats
R package. We refer users to the invitroTKstats
R package and invitrotkstats_dataproc
GitHub pages to obtain the latest version of the package and original
raw data/processing scripts, respectively.
If you are interested in contributing or want to report a bug, please submit an issue or start a discussion.
::install_github("https://github.com/USEPA/invitroTKdata") devtools
Installing a local clone of the GitHub repo:
invitroTKdata
.git clone https://github.com/USEPA/invitroTKdata
.::install_local(
devtools"<file_path_to_invitroTKdata_repo>/invitroTKdata"
)
Installing a tarball version of the package:
R CMD INSTALL <file_path_to_invitroTKdata_tarball>/invitroTKdata_X.Y.Z.tar.gz
NOTE: “X.Y.Z” in the tarball filename indicates the version number associated with the version of the package you wish to install.
To load the invitroTKdata
data R package into your local
R session via the R console:
library(invitroTKdata)
Check the package version installed and in use:
packageVersion("invitroTKdata")
The United States Environmental Protection Agency (EPA) GitHub project code is provided on an “as is” basis and the user assumes responsibility for its use. EPA has relinquished control of the information and no longer has responsibility to protect the integrity, confidentiality, or availability of the information. Any reference to specific commercial products, processes, or services by service mark, trademark, manufacturer, or otherwise, does not constitute or imply their endorsement, recommendation or favoring by EPA. The EPA seal and logo shall not be used in any manner to imply endorsement of any commercial product or activity by EPA or the United States Government.