Bayesian Optimal Phase II Design with Futility and Efficacy
Stopping Boundaries
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Documentation for package ‘BOP2FE’ version 1.0.3
Help Pages
| BOP2FE_binary | BOP2-FE design for binary endpoint |
| BOP2FE_coprimary | BOP2-FE design for co-primary endpoint |
| BOP2FE_jointefftox | BOP2-FE design for joint efficacy and toxicity endpoint |
| BOP2FE_nested | BOP2-FE design for nested (ordinal) endpoint |
| get_boundary_binary | Boundary values for binary Endpoint |
| get_boundary_coprimary | Boundary values for co-primary Endpoint |
| get_boundary_jointefftox | Boundary values for joint Endpoint |
| get_boundary_nested | Boundary values for Nested Endpoint |
| get_oc_binary | Operating characteristics for binary Endpoint |
| get_oc_coprimary | Operating characteristics for for coprimary Endpoint |
| get_oc_jointefftox | Operating characteristics for for joint Endpoint |
| get_oc_nested | Operating characteristics for Nested Endpoint |
| plot.bop2fe | Plot the cut-off probability and simulation results for BOP2FE designs |
| simulate_oc | Compute operating characteristics at the optimal boundary |
| summary.bop2fe | summarize main results for a given BOP2FE designs |