Genome-Wide Robust Analysis for Biobank Data (GRAB)

Documentation for package ‘GRAB’ version 0.2.4

CCT	Cauchy Combination Test for p-value aggregation
getPairwiseIBD	Calculate Pairwise IBD (Identity By Descent)
getSparseGRM	Make a 'SparseGRMFile' for 'GRAB.NullModel'.
getTempFilesFullGRM	Make temporary files to be passed to function 'getSparseGRM'.
GRAB.getGenoInfo	Get allele frequency and missing rate information from genotype data
GRAB.makePlink	Convert genotype matrix to PLINK format files
GRAB.Marker	Perform single-marker association tests using a fitted null model
GRAB.NullModel	Top-level API for generating a null model object used by GRAB.Marker and GRAB.Region
GRAB.POLMM	Instruction of POLMM method
GRAB.POLMM.Region	Instruction of POLMM-GENE method
GRAB.ReadGeno	Read genotype data from multiple file formats
GRAB.Region	Perform region-based association tests
GRAB.SAGELD	SAGELD method in GRAB package
GRAB.SimubVec	Simulate random effects based on family structure
GRAB.SimuGMat	Simulate genotype data matrix for related and unrelated subjects
GRAB.SimuGMatFromGenoFile	Simulate genotype matrix from external genotype file
GRAB.SimuPheno	Simulate phenotypes from linear predictors
GRAB.SPACox	Instruction of SPACox method
GRAB.SPAGRM	Instruction of SPAGRM method
GRAB.SPAmix	Instruction of SPAmix method
GRAB.WtCoxG	Instruction of WtCoxG method
SAGELD.NullModel	Construct SAGELD/GALLOP null model from a mixed-effects fit
SPAGRM.NullModel	Fit SPAGRM null model from residuals and relatedness inputs