Package: PRSPGx
Type: Package
Title: Construct PGx PRS
Version: 0.2.0
Authors@R: c(person("Song", "Zhai", role = c("aut", "cre"), email =
    "zsviolet1993@gmail.com")) 
Maintainer: Song Zhai <zsviolet1993@gmail.com>
Description: Construct pharmacogenomics (PGx) polygenic risk score (PRS) with PRS-PGx-Unadj (unadjusted), PRS-PGx-CT (clumping and thresholding), PRS-PGx-L, -GL, -SGL (penalized regression), PRS-PGx-Bayes (Bayesian regression). Package is based on ''Pharmacogenomics Polyenic Risk Score for Drug Response Prediction Using PRS-PGx Methods'' by Zhai, S., Zhang, H., Mehrotra, D.V., and Shen, J., 2021 (submitted).
License: GPL (>= 2)
Depends: R (>= 4.0.0)
Imports: gglasso (>= 1.5.0), SGL (>= 1.3.0), glmnet (>= 4.0.2), bigsnpr
        (>= 1.5.2), Matrix (>= 1.2.18), GIGrvg (>= 0.5.0), MCMCpack (>=
        1.4.6), bdsmatrix (>= 1.3.4), bigsparser (>= 0.4.0), lmtest (>=
        0.9.37), mvtnorm (>= 1.1.0), propagate (>= 1.0.6), bigparallelr
        (>= 0.2.3), methods (>= 3.6.3), bigstatsr (>= 1.2.3), Rfast (>=
        1.9.9), matrixcalc (>= 1.0-3)
Suggests: knitr, rmarkdown
VignetteBuilder: knitr
Encoding: UTF-8
LazyData: true
RoxygenNote: 7.1.2
NeedsCompilation: yes
Packaged: 2022-06-16 16:10:37 UTC; zhaiso
Author: Song Zhai [aut, cre]
Repository: CRAN
Date/Publication: 2022-06-16 17:30:02 UTC
