Package: dfpk
Type: Package
Title: Bayesian Dose-Finding Designs using Pharmacokinetics(PK) for
        Phase I Clinical Trials
Version: 3.3.1
Date: 2017-06-30
Author: Artemis Toumazi <artemis.toumazi@inserm.fr>, Moreno Ursino <moreno.ursino@inserm.fr> 
		and Sarah Zohar <sarah.zohar@inserm.fr>
Maintainer: Artemis Toumazi <artemis.toumazi@inserm.fr>
Description: Statistical methods involving PK measures are provided, in the dose allocation 
						process during a Phase I clinical trials. These methods enter pharmacokinetics 
						(PK) in the dose finding designs in different ways, including covariates models,
						dependent variable or hierarchical models. 
						This package provides functions to generate data from several scenarios and functions 
						to run simulations which their objective is to determine the maximum tolerated dose (MTD).
License: GPL (>= 3) | file LICENSE
Depends: R (>= 3.0.2), Rcpp (>= 0.12.0), rstan (>= 2.12.1)
Imports: ggplot2 (>= 2.0.0), dfcrm, methods, stats, graphics,
        grDevices, PK
LinkingTo: StanHeaders (>= 2.12.0), rstan (>= 2.12.1), BH (>= 1.60),
        Rcpp (>= 0.12.0), RcppEigen
RcppModules: stan_fit4logit_reg_pkcov_mod, stan_fit4cdf_reg_dtox_mod,
        stan_fit4logit_reg_pkpop_mod, stan_fit4cdf_reg_pktox_mod,
        stan_fit4logit_reg_pklogit_mod, stan_fit4reg_auc_mod
SystemRequirements: C++11
LazyData: true
NeedsCompilation: yes
URL: http://github.com/artemis-toumazi/dfpk
BugReports: http://github.com/artemis-toumazi/dfpk/issues
RoxygenNote: 6.0.1
Packaged: 2017-06-30 10:15:14 UTC; artemistoumazi
Repository: CRAN
Date/Publication: 2017-06-30 13:28:18 UTC
