NAPrior: Network Meta-Analytic Predictive Prior for Mid-Trial SoC Changes
Implements the Network meta-Analytic Predictive (NAP) prior framework to
accommodate changes in the standard of care (SoC) during ongoing randomized controlled
trials (RCTs). The method synthesizes pre- and post-change in-trial data by leveraging
external evidence, particularly head-to-head trials comparing the original and new
standards of care, to bridge the two evidence periods and enable principled borrowing.
The package provides utilities to construct NAP-based priors and perform Bayesian
inference for time-to-event endpoints using summarized trial evidence.
| Version: |
0.1.1 |
| Depends: |
R (≥ 4.0) |
| Imports: |
stats, graphics, survival, R2jags, metafor, purrr, dplyr, tibble |
| Suggests: |
rjags, knitr, rmarkdown |
| Published: |
2026-01-20 |
| DOI: |
10.32614/CRAN.package.NAPrior (may not be active yet) |
| Author: |
Chunyi Zhang [aut, cre] |
| Maintainer: |
Chunyi Zhang <czhang12 at mdanderson.org> |
| License: |
MIT + file LICENSE |
| NeedsCompilation: |
no |
| Materials: |
README, NEWS |
| CRAN checks: |
NAPrior results |
Documentation:
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